Aerosol uptake and biomarker of exposure - processed

This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague Dawley rats were exposed of either aerosols of the mentholated version of the tobacco heating system 2.2 (THS2.2M) or smoke of 2 two mentholated reference cigarettes (MRC(LM) and MRC(HM)) in comparison with 3R4F cigarette smoke. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Biomarkers of exposure, including markers of exposure in blood, plasma and urine were measured.
This dataset includes descriptive statistics at the group level.