Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4zvv
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资源简介：
Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140 Descriptor: (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Li, Y, Chen, Z, Eigenbrot, C. Deposit date: 2015-05-18 Release date: 2016-05-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition. Nat.Chem.Biol., 12, 2016
创建时间：
2015-05-18
