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Crystal Structure of the second bromodomain of human BRD2 in complex with the compound 3b

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal Structure of the second bromodomain of human BRD2 in complex with the compound 3b Descriptor: 1,2-ETHANEDIOL, 2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-((1-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamido)butyl)-1H-1,2,3-triazol-4-yl)methyl)acetamide, Bromodomain-containing protein 2 Authors: White, S.W, Yun, M. Deposit date: 2020-05-08 Release date: 2021-11-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.31 Å) Cite: Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. Angew.Chem.Int.Ed.Engl., 60, 2021
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2020-05-08
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