Expression Patterns of Non-Alcoholic Fatty Liver Disease genes and Efficacy of Green Tea on Hyperlipidemic Animal Model. Mus musculus

Currently, there are no established treatments for NAFLD/NASH. Treatment recommendations include weight reduction through both diet and physical exercise, and weight-loss surgery for extreme obesity. Most medical regimens target components of the metabolic syndrome or oxidative stress associated with the pathogenesis of NASH. These include anti-obesity regimens, insulin sensitizers, anti-hyperlipidemics, and antioxidants. Thus, a need exists to validate approaches that might help the development and progression of hepatic steatosis, oxidative stress, and inflammation in association with NAFLD. Overall design: Total RNA was extracted from liver tissues of treated and untreated (NAFLD) groups and submitted for whole genome expression analysis.