BTK kinase domain with inhibitor 1
收藏Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5fbn
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资源简介：
BTK kinase domain with inhibitor 1 Descriptor: 1,2-ETHANEDIOL, 4-[8-azanyl-3-[(2~{S})-1-[4-(dimethylamino)butanoyl]pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-(1,3-thiazol-2-yl)benzamide, 4-[8-azanyl-3-[(3~{R})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-[4-(trifluoromethyl)pyridin-2-yl]benzamide, ... Authors: Raaijmakers, H.C.A, Vu-Pham, D. Deposit date: 2015-12-14 Release date: 2016-02-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis. Acs Med.Chem.Lett., 7, 2016
创建时间：
2015-12-14
