Drug administration route as a key driver for the immediate outcomes of 10-day vancomycin treatment on fecal microbiome, viral communities, serum metabolome, and immune factors in rats

In this study, a rat model was used to assess the effects of a 10-day treatment with different routes of administration on the structural and functional potential of the host fecal microbiome, resistome, serum metabolome, SCFA, and immune indicators.