Critical Requirement of the DNA Methyltransferase, Dnmt1, for the Development and Function of Foxp3+ Regulatory T Cells

ChEBI2013-04-21 更新2026-07-21 收录

免疫表观遗传学

调节性T细胞功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-27434 数据链接链接失效反馈

官方服务：

资源简介：

Critical Requirement of the DNA Methyltransferase, Dnmt1, for the Development and Function of Foxp3+ Regulatory T Cells

创建时间：

2013-04-21

Table_4_Role of Immune Cell-Specific Hypermethylation Signatures in Classification and Risk Stratification of Breast Cancer.xlsx

乳腺癌预后

免疫表观遗传学

Background: Epigenetic regulation, including DNA methylation, plays a major role in shaping the identity and function of immune cells. Innate and adaptive immune cells recruited into tumor tissues con

NIAID Data Ecosystem90

Table_2_Arabidopsis SDG8 Potentiates the Sustainable Transcriptional Induction of the Pathogenesis-Related Genes PR1 and PR2 During Plant Defense Response.XLSX

免疫表观遗传学

防御基因转录调控

Post-translational covalent modifications of histones play important roles in modulating chromatin structure and are involved in the control of multiple developmental processes in plants. Here we prov

NIAID Data Ecosystem50

Longitudinal Analysis of Influenza Vaccines on DNA methylation Identifies the RIG-I Signaling Pathway. Longitudinal Analysis of Influenza Vaccines on DNA methylation Identifies the RIG-I Signaling Pathway

免疫表观遗传学

疫苗效果评估

Influenza virus infection was previously found to alter the promoter DNA methylation of key immune response-related genes, including type-1 interferons and proinflammatory cytokines. However, less is

NIAID Data Ecosystem30

Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function [ATAC-Seq]. Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function [ATAC-Seq]

调节性T细胞功能

转录调控机制

We investigated the role of Ikaros in regulatory Tcell identity and function during stimulation using RNA-seq, ATAC-seq, and H3K27ac/Foxp3/Ikzf1 ChIP-seq Overall design: We performed ATAC-seq, RNA-seq

NIAID Data Ecosystem80

Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells

调节性T细胞功能

自身免疫疾病机制

BackgroundCD4+CD25+FOXP3+ Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in

NIAID Data Ecosystem40

Critical Requirement of the DNA Methyltransferase, Dnmt1, for the Development and Function of Foxp3+ Regulatory T Cells

资源简介：

相关数据集