Detection of differentially expressed transcripts and polymorphisms associated with disease resistance in rohu carp (Labeo rohita, Hamilton) using Illumina mRNA-seq and selective RNA pooling

An integrated approach was used to identify genes associated with resistance to Aeromonas hydrophila, an important bacterial pathogen causing aeromoniasis in rohu (Labeo rohita). DNA polymorphism and gene expression profiling in lines of L. rohita selected for resistance or susceptibility to challenge with A. hydrophila, and grown in a common environment, were studied using Illumina mRNA-seq of selectively pooled RNA samples.