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miR-seq to define mature miRNAs in human HEK293T cells that are targeted for degradation by the endonuclease Tudor-SN (i.e. by TumiD).

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NIAID Data Ecosystem2026-03-11 收录
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We report that human Tudor-SN degrades particular miRNAs that contain CA or UA dinucleotides located more than five nucleotides from miRNA ends. We defined miRNAs that are degraded by Tudor-SN by performing miR-seq on RNA isolated from HEK293T cells transiently transfected with Tudor-SN siRNA or, as a control, Control (Ctl) siRNA.

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2019-05-15
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