Escherichia coli strain:PSUO78 | isolate:PSUO78 Genome sequencing and assembly. Escherichia coli strain:PSUO78 | isolate:PSUO78

Layer peritonitis is considered a major cause of morbidity and mortality in laying hens which leads to significant economic losses to the table egg industry worldwide. Escherichia coli is the most common bacterial species associated with layer peritonitis. Despite its importance to the poultry industry, pathogenesis of layer peritonitis has not been elucidated. The objectives of the current study are; 1) to identify potential virulence factors encoded in E. coli causing peritonitis using whole genome sequencing, 2) ascertain genotypic homology among avian pathogenic E. coli and human extraintestinal pathogenic E. coli by comparative genomics, and 3) to identify potential vaccine targets through antigenome approaches