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Investigating the role of FOS/AP-1 in OnF reprogramming during tumor intiation. Investigating the role of FOS/AP-1 in OnF reprogramming during tumor intiation

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the role of FOS/AP-1 in early OnF reprogramming, we blocked its activity during tumor intiation by overexpressing a dominant negative form of FOS. Overall design: We overexpressed a dominant negative form of FOS in APCflox/flox organoids, which were then terated with OHT to iduce APC Loss-of-function.

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2024-04-02
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