Comparative viral pathogenesis between intranasal and ocular inoculation day 3 p.i. in ocular tissue.

aLimit of detection is 1.5 log10 EID50 (eye and conj) or 0.8 log10 EID50 (CW, all 100 µl i.n. samples). The mean viral titer of all ferrets with positive virus isolation (denoted in parentheses) is shown.bRoute of inoculation. i.n., intranasal (106 EID50/ml) unless otherwise specified; i.o.; ocular inoculation (106 EID50/100 µl).cRelative viral RNA copy number in CW samples determined by RT-PCR and extrapolated using a standard curve of known virus. i.o. CW samples are inclusive of 6 ferrets tested.dIntranasal inoculation performed using 106 EID50/100 µl virus dose.eND, not detected.