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The crystal structure of Human VPS34 in complex with PIK-III

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Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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The crystal structure of Human VPS34 in complex with PIK-III Descriptor: 4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 Authors: Knapp, M.S, Elling, R.A. Deposit date: 2014-05-04 Release date: 2014-10-29 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat.Cell Biol., 16, 2014
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2014-05-04
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