Potential Anti-Tumor Drug: Co-Crystal 5‑Fluorouracil-nicotinamide
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https://figshare.com/articles/dataset/Potential_Anti-Tumor_Drug_Co-Crystal_5_Fluorouracil-nicotinamide/12559049
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资源简介：
5-Fluorouracil-nicotinamide (5-FU-NCM), a co-crystal with a 2D
layer structure formed by hydrogen bonds, was synthesized by solvent
evaporation and liquid phase-assisted grinding at room temperature.
Compared to 5-FU alone, the results of solubility, oil–water
partition coefficient, anti-tumor effect in vivo and vitro, acute
toxicity, and pharmacokinetic parameters indicate that the co-crystal
is a potential anti-tumor drug.
创建时间：
2020-06-24
