Prkar1b

ENCODES a protein that exhibits cAMP binding; cAMP-dependent protein kinase regulator activity; cAMP-dependent protein kinase inhibitor activity (ortholog); INVOLVED IN positive regulation of excitatory postsynaptic potential; positive regulation of fear response; positive regulation of long-term synaptic potentiation; PARTICIPATES IN protein kinase A (PKA) signaling pathway; ASSOCIATED WITH abnormal excitatory postsynaptic potential; decreased freezing behavior; increased thermal nociceptive threshold; ASSOCIATED WITH Tremor; Emery-Dreifuss muscular dystrophy (ortholog); hypertension (ortholog); FOUND IN cAMP-dependent protein kinase complex; cytoplasm (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine

编码一种具有cAMP结合能力的蛋白质；cAMP依赖性蛋白激酶调节活性；cAMP依赖性蛋白激酶抑制活性（同源）；参与兴奋性突触后电位的正向调节；恐惧反应的正向调节；长期突触效能增强的正向调节；参与蛋白激酶A（PKA）信号通路；与异常兴奋性突触后电位相关；冻结行为减少；热痛觉阈值增加；与震颤相关；Emery-Dreifuss肌肉萎缩症（同源）；高血压（同源）；存在于cAMP依赖性蛋白激酶复合物中；细胞质（同源）；谷氨酸能突触（同源）；与1-萘基异硫氰酸酯、17β-雌二醇、2,3,7,8-四氯二苯并-对-二恶英相互作用。