Knockdown resistance (kdr) mutations in 17 field populations of A. albopictus from Beijing China: first report of novel V1016G mutation and evolutionary origins of kdr haplotypes

Partial DNA sequences of domain II and domain III of Ae. albopictus voltage gated sodium channel (VGSC) gene were amplified from a total of 426 individuals, collected from 17 sites in the Beijing municipality. These DNA fragments were sequenced to discover the possible genetic mutations mediating knockdown resistance (kdr) to pyrethroids. The frequency and distribution of kdr mutations were assessed in the 17 Ae. albopictus populations. (MapVEu VBP0000474)