Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice [genomicDNA]
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP413102
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资源简介：
We assessed genome editing strategies to treat cardiomyopathy in mice including one or two doses of ABE8e, or one low, medium, or high dose of SaCas9 nuclease We conducted RNA analysis and genomic DNA analysis at the target region and transcriptome-wide analysis to assess cellular phenotypes Overall design: After genomic DNA extraction from mouse tissues, the a 300 bp region around the target editing site (Myh6 R403Q ) was PCR-amplified and sequenced on an Illumina MiSeq
创建时间：
2023-03-15
