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Transcription profiling by array of human melanoma cells with doxycycline-inducible RNAi-mediated knockdown of B-Raf

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https://www.omicsdi.org/dataset/biostudies-other/S-ECPF-GEOD-13487
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Unsupervised hierarchical clustering revealed a strong similarity in gene modulation resulting from either compound treatment or BRAF ablation mediated by RNA interference relative to DMSO-treated control samples . Experiment Overall Design: We have generated melanoma A375 cells stably expressing a shRNA construct for doxycycline-inducible knockdown of B-Raf (2 mg/ml Dox, 48h). Small molecule treatment was at 1000nM R341787, 24h.
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2016-04-14
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