In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a
Pentachlorophenol (PCP) is a highly toxic pesticide that was first introduced in the 1930s. The a-proteobacterium Sphingobium chlorophenolicum, which was isolated from PCP-contaminated sediment, has a
DNA methylation has been utilized for target gene silencing in plants, however it’s not well-understood whether other silencing pathways can be also used to manipulate gene expression. Here we perform
