HNP-1 potentiates HIV-1 inhibition by peptides targeting the gp41 N-HR domain.

Fusion experiments between HXB2 (A, C) and BaL (B, D) pseudoviruses and TZM-bl cells were performed as described in the legend to Figure 2, using varied concentrations of C34 (A, B) or N36mut(e,g) (C, D) in the presence (red symbols) or in absence (black symbols) of 7.3 µM HNP-1 in HBSS supplemented with 10% human serum. Data points are means and SEM from a representative triplicate experiment; the solid lines are obtained by curve-fitting, as described above. See Table 2 for the respective IC50 values.