Reproducibility package for: A Platelet Activation Gene Signature Predicts Mortality in Pneumonia-Induced Sepsis

This Zenodo record provides code and derived data to reproduce the analyses and figures reported in the manuscript:“A Platelet Activation Gene Signature Predicts Mortality in Pneumonia-Induced Sepsis: A Multi-Cohort Transcriptomic Analysis.” Source (raw) transcriptomic datasets are publicly available at:- GEO: GSE65682- BioStudies: E-MTAB-4421 and E-MTAB-4451 Contents of this record:- code/: scripts for data processing, model development (pathway-constrained LASSO-penalized Cox regression), validation, and figure generation- results/: model coefficients for the three-gene signature (MAP3K7CL, SEPP1, WFDC1), risk score computation notes, and key result tables used in the manuscript figures- env/: software environment information (e.g., sessionInfo / requirements)- README.md: step-by-step instructions to download the public datasets and reproduce the main results Intended use:The materials are provided for transparency and reproducibility. No individual-level identifying information is included.