Supporting Information S1 - Deep Sequencing Analysis of HCV NS3 Resistance-Associated Variants and Mutation Linkage in Liver Transplant Recipients

Combined Supporting Information file containing supplementary methods, tables and figures. Supplementary methods include information on RNA isolation, primer design/RT-PCR amplification, RNA transcript/mock community construction, population/clonal sequencing, pyrosequencing platforms, and bioinformatics processing. Supplementary tables include information on primers, read filtering, variant frequencies, and alpha diversity. The supplementary figure covers quasispecies evolution and dynamics in liver transplant recipients. (PDF)