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Adaptive Shifts in Gene Regulation Underlie a Developmental Delay in Thermogenesis in High-Altitude Deer Mice

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NIAID Data Ecosystem2026-03-12 收录
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We sequenced skeletal muscle and brown adipose tissue transcriptomes of deer mice (Peromyscus maniculatus) across a critical post-natal developmental window. We determined the regulatory basis of evolutionary changes in the development of thermogenesis (a performance metric critical to survival) in a lab-raised high-altitude population of deer mice, compared to a lowland population thought to represent the ancestral state.

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2020-09-28
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