A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders Descriptor: (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E Authors: Papadopoulos, E. Deposit date: 2021-04-07 Release date: 2021-04-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.91 Å) Cite: A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders. Eur.J.Med.Chem., 219, 2021
创建时间：
2021-04-07
