Data of Baicalin
收藏NIAID Data Ecosystem2026-03-11 收录
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Results
1. Effects of Baicalin on cell viability and LDH production
Note:
RAW264.7 cells viability——RAW细菌感染细胞活性
H9 cells viability——H9细菌感染细胞活性
1——control group;2——S. typhimurium group;3,4,5——S. typhimurium + Baicalin (25, 50, 100 μmol/L) group; 6——100 μmol/L Baicalin group
Note:
LDH of RAW264 cells——LDHRAW264
LDH of H9 cells cells——LDHH9
1——control group;2——S. typhimurium group;3,4,5——S. typhimurium + Baicalin (25, 50, 100 μmol/L) group; 6——100 μmol/L Baicalin group
2. Effects of Baicalin on bactericidal effect
Note:
Bactericidal effect——rateofkilling
1——S. typhimurium group;2,3,4——S. typhimurium + Baicalin (25, 50, 100 μmol/L) group.
3. Effects of Baicalin on inflammatory cytokines and oxidative stress induced by S. typhimurium
Note:
The levels of TNF-α——TNFz;The levels of IL-1β——IL1z;The levels of IL-6——IL6z;The levels of IL-8——IL8z
1——control group;2——S. typhimurium group;3,4,5——S. typhimurium + Baicalin (25, 50, 100 μmol/L) group; 6——100 μmol/L Baicalin group
ROS production——ROS
1——control group;2——S. typhimurium group;3,4,5——S. typhimurium + Baicalin (25, 50, 100 μmol/L) group; 6——100 μmol/L Baicalin group
4. Baicalin mediated the autophagy and activation of TLR4 pathway induced by S. typhimurium
Note:
LC3 immuno-positive cells——荧光百分率
1——control group;2——S. typhimurium group;3——S. typhimurium + Baicalin (100 μmol/L) group; 4——100 μmol/L Baicalin group
the expression of LC3-II/I——LC3;the expression of Beclin 1——Beclin 1
1——control group;2——S. typhimurium group;3——S. typhimurium + Baicalin (100 μmol/L) group; 4——100 μmol/L Baicalin group
the expression of TLR4, p-p38/p38, p-JNK/JNK, p-ERK/ERK——TLR4, p38, JNK, ERK
1——control group;2——S. typhimurium group;3——S. typhimurium + Baicalin (100 μmol/L) group; 4——100 μmol/L Baicalin group
5. Effects of Baicalin on S. typhimurium-induced autophagy and activation of TLR4 pathway in TLR4 overexpression
Note:
the expression of TLR4——pcDNATLR4
1——pcDNA3.1(+) group;2——pcDNA3.1-TLR4 group;
the expression of LC3, Beclin1, TLR4, p-p38/p38, p-JNK/JNK, p-ERK/ERK——LC32, Beclin12, TLR42, p382, JNK2, ERK2
1——pcDNA3.1(+)-S. typhimurium group;2——pcDNA3.1(+)-S. typhimurium + Baicalin group; 3—— pcDNA3.1-TLR4 -S. typhimurium group;4——pcDNA3.1-TLR4 -S. typhimurium + Baicalin group
创建时间:
2020-06-30



