Whole genome sequencing to investigate Cryptosporidium hominis IbA10G2 from epidemic and background cases. Cryptosporidium hominis

In summer 2015 there was an excess of Cryptosporidium cases in the UK that peaked in week 38. No particular age group or sex was involved, and although a greater proportion than expected had travelled to Spain this did not explain the magnitude of the increase. Most cases were C. hominis, gp60 genotype was IbA10G2, which is highly prevalent in northern Europe. No particular exposures were identified from enhanced surveillance and there was no obvious explanation. To investigate the relationship between isolates contributing to the epidemic, whole genome sequencing was used.