Genome-wide mapping implicates R-loops in lineage-specific processes and DNA break hotspot formation in neural stem/progenitor cells
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https://www.ncbi.nlm.nih.gov/sra/SRP357831
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资源简介:
We elucidated the genome-wide landscape of RNA:DNA hybrid structures called "R-loops" in primary neural stem/progenitor cells to assess their contribution to recurrent classes of DNA break "hotspots". Overall design: We performed genome-wide mapping of RNA-DNA hybrids in mouse primary neural stem/progenitor cells via DRIP-seq.
创建时间:
2022-08-17



