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Transcriptional profiling by array of ovaries from aged mice

Alliance of Genome Resources2026-08-01 收录

卵巢衰老机制

卵巢老化标志物

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http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=E-MTAB-7493 数据链接链接失效反馈

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We transcriptionally profiled ovaries harvested from young and middle-aged outbred CD1 mice to elucidate mechanisms and identify novel markers of ovarian aging.

应用场景：

卵巢衰老机制

单核多组学

The ovary is the first organ to age in the human body, affecting both fertility and overall health. However, the biological mechanisms underlying human ovarian aging remain poorly understood. Here we

NIAID Data Ecosystem20

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

卵巢衰老机制

单细胞转录组学

Molecular mechanisms of ovarian aging and female age-related fertility decline remain unclear. We surveyed the single-cell transcriptomic landscape of ovaries from young and aged non-human primates (N

NIAID Data Ecosystem10

NADase CD38 is a key determinant of ovarian lifespan

卵巢衰老机制

生殖细胞转录组

The ovary ages earlier than most other tissues in women, yet the underlying biological mechanisms and strategies to delay ovarian aging remain enigmatic. In this study, a comprehensive analysis of tra

NIAID Data Ecosystem00

Spatial transcriptomics of the ageing ovary

卵巢衰老机制

空间转录组学

Ageing is a physiological process that manifests through progressive molecular, cellular, and systemic changes. Female reproductive potential gradually declines with age as oocyte quality and quantity

NIAID Data Ecosystem10

Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice

卵巢衰老机制

抗衰老药物

Ovarian aging is characterized by declines in follicular reserve and the emergence of mitochondrial dysfunction, reactive oxygen species production, inflammation, and fibrosis, which eventually result

NIAID Data Ecosystem00

Transcriptional profiling by array of ovaries from aged mice

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