The fibrinogen-bound integrin alphaIIb beta3 clusters platelets together to form a platelet plug and generates intracellular signals (outside-in) causing further platelet activation and platelet plug

reactome.org110

Data from: Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum

疟疾研究

血小板生物学

Platelets restrict the growth of intraerythrocytic malaria parasites by binding to parasitized cells and killing the parasite within. Here, we show that the platelet molecule platelet factor 4 (PF4 or

Research Data Australia80

Immobilized collagen prevents shedding and induces sustained GPVI clustering and signaling in platelets

血小板生物学

细胞信号传导

Collagen, the most thrombogenic constituent of blood vessel walls, activates platelets through glycoprotein VI (GPVI). In suspension, following platelet activation by collagen, GPVI is cleaved by A Di

DataCite Commons2022-01-31 更新50

Taking the stock of granule cargo: Platelet releasate proteomics

血小板生物学

蛋白质组学

Human platelets are key players in a multitude of physiological and pathological processes. Upon activation they release cargo from different types of granules as well as microparticles in an apparent

DataCite Commons2020-09-03 更新110

Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity

血小板生物学

tRNA动态

Previous investigations have indicated that RNAs are mostly present in the minor population of the youngest platelets, whereas translation in platelets could be biologically important. To attempt to s

NIAID Data Ecosystem70

https://doi.org/10.7554/eLife.91757.1

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