File S1 - Culture-Independent Evaluation of the Appendix and Rectum Microbiomes in Children with and without Appendicitis

This file contains Figure S1–Figure S3. Figure S1, Bacterial Community Richness and Diversity Estimators by Sample. The figure shows, for each sample, the sample type (appendix or rectum), the diagnosis (normal, appendicitis, perforated appendicitis), the observed number of OTUs, and the Chao1, ACE (richness), Shannon (diversity), and Simpson values. Figure S2, Bacterial community composition at the phylum level. The figure shows the bacterial relative abundance (fraction of total sequence reads assigned to each of the bacteria phyla listed in the legend on the right side) for each of the samples studied. The sample names follow the convention used in Figure 1: Samples are listed by ID number, SnX/Y, where n is the subject identification number, X describes the body site (A for appendix, R for rectum), and Y describes the patient's diagnosis (N for normal appendix, NP for an appendix with non-perforating appendicitis, and P for an appendix with perforating appendicitis). Figure S3, Bacterial community composition at the genus level. The figure shows the bacterial relative abundance (fraction of total sequence reads assigned to each of the bacteria genera listed in the legend on the right side). The sample names follow the convention used in Figure 1: Samples are listed by ID number, SnX/Y, where n is the subject identification number, X describes the body site (A for appendix, R for rectum), and Y describes the patient's diagnosis (N for normal appendix, NP for an appendix with non-perforating appendicitis, and P for an appendix with perforating appendicitis).
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