Dataset from: 5-Methoxytryptophan attenuates inflammatory pain, modulates peripheral serotonin-immune signatures, and restores central serotonin transporter availability in male rats
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This dataset contains the processed RNA-seq count matrix and metadata, animal-level behavioral and paw-thickness source data, SERT PET region-of-interest (ROI) source data, all figure source tables, full gene-set/module membership definitions, and software-version information required to reproduce the figures and statistics reported in the associated manuscript "5-Methoxytryptophan attenuates inflammatory pain, modulates peripheral serotonin-immune signatures, and restores central serotonin transporter availability in male rats" (submitted to Brain, Behavior, and Immunity - Health). Contents:- Data Sheets S1–S2: RNA-seq metadata and count data- Data Sheets S3–S9: Figure 2 source tables (PBMC inflammatory-neuroimmune signatures)- Data Sheets S10–S12: Figure 3 rescue tables (M50 reversal of CFA-induced changes)- Data Sheets S13–S15: Figure 4 serotonin-tryptophan-neuroimmune tables- Data Sheets S16–S18: Figure 5 inflammatory and composition-sensitive module tables- Data Sheets S19–S23: Figure 6 animal-level behavioral endpoint tables- Data Sheets S24–S28: Figure 7 SERT PET and behavior-concordance tables- Data Sheet S29: Full gene-set/module membership definitions Raw RNA-seq sequencing data are separately deposited in NCBI GEO (accession number to be added).



