Superoxide in the SN dopaminergic neurons.

Confocal quantitation of relative mitosox-red fluorescence intensity in SN DA neurons in untreated (ND) or dox-treated (D) transgenic mice in the absence or presence of deprenyl (DD) or EUK-189 (DEUK). Confocal images from immunofluorescent sections of brains were obtained following various treatment regimes and subjected to intensity measurements using the IMARIS software suite (Bitplane AG, Zurich, Switzerland) on selected cells from multiple sections from each treatment. Data is presented both as mean pixel intensity and total red fluorescent pixels (mitosox red) per cell.