Neuro 2A Transcriptome or Gene expression
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP471232
下载链接
链接失效反馈官方服务：
资源简介：
5-methylcytosine dioxygenase 3 (TET3) is a member of the Ten-Eleven-Translocation (TET) family of enzymes shown to mediate DNA demethylation by oxidising 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) and further oxidative intermediates. 5-hmC is a stable DNA modification associated with actively transcribed euchromatin and thus may serve as a mechanism underlying the activation of lineage-specific transcriptional programmes. TET3, specifically, has been proven to be highly expressed in neurons. Nevertheless, the molecular mechanisms which underlie the role(s) it plays in brain function such as its plasticity are yet to be discovered.
创建时间：
2023-11-10
