Selective eradication of leukemia cells with reprogramming factors (ATAC-Seq)
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https://www.ncbi.nlm.nih.gov/sra/SRP165195
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资源简介：
We used ATAC-seq to evaluate the global programme of chromtain accessibility after Dox inducible Yamanaka factors ectopic expression during this biological process. Overall design: To investigate the chromatin accessibility changes for the elimination of leukemia cells after Dox inducible Yamanaka factors (Oct4,Sox2,Klf4,c-Myc) expression, we sorted GFP+ MLL-AF9 acute myeloid leukemia cells (MLL-AF9) from leukemic mice and normal c-kit+ cells (WT) from 4F transgenic mice. Leukemia cells and ckit+ cells were sorted from distinct groups at different time points
创建时间：
2019-12-18
