Supplementary material: Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study

These are peer-reviewed supplementary materials for the article 'Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study' published in the Journal of Comparative Effectiveness Research.Supplementary Figure S1Supplementary Figure S2Supplementary Table S1Supplementary Table S2Supplementary Table S3Aim: This online interactive survey investigated lipid-lowering approaches of French cardiologists in high and very high-cardiovascular risk patients with hypercholesterolemia. Materials & methods: Physicians assessed three hypothetical patients at three clinic visits, and selected the patients’ cardiovascular risk category, target low-density lipoprotein cholesterol (LDL-C) and treatment. Results: A total of 162 physicians completed 480 risk assessments; 58% of assessments correctly categorized the hypothetical patients. Most physicians chose the correct LDL-C target for one of the very high-risk patients, but higher than recommended targets were selected for the other very high-risk patient and the high-risk patient. Statins were the most commonly chosen treatment. Conclusion: French cardiologists often underestimate cardiovascular risk in patients with hypercholesterolemia, select a higher-than-recommended LDL-C target and prescribe less intensive treatment than that recommended by guidelines.

本数据集为发表于《比较疗效研究杂志》的论文《法国心脏病学家对高危患者高胆固醇血症管理的评估：基于病例摘要的研究》的同行评审补充材料。补充图表S1、补充图表S2、补充表格S1、补充表格S2、补充表格S3。目的：本在线交互式调查探讨了法国心脏病学家在针对高心血管风险和极高心血管风险的高胆固醇血症患者中采用的降脂策略。材料与方法：医师对三位假设患者在三次门诊访问中进行了评估，并选择了患者的 cardiovascular risk category（心血管风险类别）、目标低密度脂蛋白胆固醇（LDL-C）和治疗方案。结果：共有162名医师完成了480次风险评估；其中58%的风险评估正确地将假设患者分类。大多数医师为极高风险患者之一选择了正确的LDL-C目标值，但对于另一位极高风险患者和高风险患者，选择了高于推荐的目标值。他汀类药物是最常选择的治疗方案。结论：法国心脏病学家往往低估了高胆固醇血症患者的 cardiovascular risk（心血管风险），选择了高于推荐的低密度脂蛋白胆固醇（LDL-C）目标值，并开具的治疗方案低于指南中推荐的治疗强度。