Experimental data of C38 mouse colon adenocarcinoma (tumor length, tumor width, tumor mass and tumor volume).

Data was measured at the final day of Phase I (24th day) and Phase III/3 (23rd day). a Directly measured data (tumor length, tumor width, tumor mass) b Estimated data (tumor volume measured by caliper, calculated according to Xenograft tumor model protocol or two-dimensional mathematical model) c MRI-measured data (tumor volume calculated with flood fill algorithm) d Evaluated data (“MRI” tumor volume calculated from linear curve fit (see Eq 8)) Experimental data of C38 mouse colon adenocarcinoma (tumor length, tumor width, tumor mass and tumor volume).