Mixed Effects Model of Evolution (MEME) results for sites with human-specific amino acid substitutions.

α, synonymous substitution rate. β-, non-synonymous substitution rate for the negative/neutral evolution component. p-, mixture distribution weight allocated to β- (i.e., the proportion of the tree neutrally of or under negative selection). β+, non-synonymous substitution rate for the positive selection/neutral component. p+, mixture distribution weight allocated to β+ (i.e., the proportion of the tree neutrally of or under positive selection). LRT, likelihood ratio test statistic for episodic diversification(i.e., p+ > 0 and β+ > α). P-value, asymptotic P-value for episodic diversification (i.e., p+ > 0 and β+ > α). # branches under selection, an estimate for how many branches may been under selection at this site. Total branch length, the total length of branches contributing to the inference at this site (used to scale dN and dS).