Bone histomorphometry in Ptpn2−/− (BALB/c) mice.

Bone volume/Trabecular bone volume (BV/TV), trabecular number (TbN), trabecular thickness (TbTh) and trabecular separation (TbSp) in 14 day-old Ptpn2+/+ (BALB/c), Ptpn2+/− (BALB/c) and Ptpn2−/− (BALB/c) mice. Osteoid surface/bone surface (OS/BS), osteoid thickness, osteoid volume/bone volume (OV/BV), osteoblast surface/bone surface (ObS/BS), osteoclast surface/bone surface (OcS/BS), number of osteoblasts/bone perimeter (Nob/BPm) and number of osteoclasts/bone perimeter (Noc/BPm) are also shown. Results shown are means ± SEM; p values are for Ptpn2+/+ versus Ptpn2−/− mice and were determined using a two-tailed Mann-Whitney U Test.