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Positional identification of Adamts16 variants linked to inherited hypertension: knockdown of Adamts16 in NRK-52E cells

Alliance of Genome Resources2026-08-01 收录

遗传性高血压基因功能

siRNA基因敲低

数据链接：

https://www.ncbi.nlm.nih.gov/gds/?term=GSE12724 数据链接链接失效反馈

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资源简介：

Keywords: Gene knockdown with siRNA

关键词：小干扰RNA（siRNA）介导的基因敲低

应用场景：

miRNA加工机制

siRNA基因敲低

We asked whether the human drosha protein, an RNase III homolog known to process microRNAs (miRNAs), might also be a small nuclear RNA (snRNA) 3' processing factor. Using retroviral siRNA silencing c

NIAID Data Ecosystem40

SF3b155 knock-down by two different siRNA oligos in HeLa cells

剪接机制调控

siRNA基因敲低

Analysis of the alternative pre-mRNA procesing after SF3b155 siRNA knock-down in HeLa cells employing a custom microarray platform sensitive to splicing. HeLa cells were transfected with either a scra

NIAID Data Ecosystem20

siRNA knockdown of GALNT1 in hepatocellular carcinoma HA22T and PLC5 cells. Homo sapiens

肝细胞癌基因功能研究

siRNA基因敲低

To determine the whole genome profile of GALNT1 silenced HA22T and PLC5 cells Overall design: HA22T and PLC5 cells were transfected with non-targeting and GALNT1 specific siRNA with Lipofectamine RNAi

NIAID Data Ecosystem20

Lambda light chain knockdown in ALMC1 human myeloma cells

多发性骨髓瘤分子机制

siRNA基因敲低

We used siRNA to knockdown lambda light chain expression in ALMC1 cells that express an intact IgG lambda monoclonal protein. We compared knockdown cells to cells treated with control siRNA.

NIAID Data Ecosystem30

siRNA induced silencing of CITED1 in HT144 human melanoma cells

黑色素瘤基因表达与功能

siRNA基因敲低

To investigate the function of CITED1 in melanoma, its expression was transiently down regulated using CITED1-targeting siRNA. The HT144 melanoma cell line was chosen as it had a relatively high level

NIAID Data Ecosystem20

Positional identification of Adamts16 variants linked to inherited hypertension: knockdown of Adamts16 in NRK-52E cells

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