Effect of SIRPA perturbation on transcriptome of B16 murine melanoma cells. Effect of SIRPA perturbation on transcriptome of B16 murine melanoma cells

To explore the effect of SIRPA perturbation on the expression changes of melanoma differentiation antigens (MDA), which directly mediates the immunogenicity of melanoma cells, we profiled the transcriptomes of B16F10 cells with SIRPA knockdown, overexpression, or control. Overall design: Total RNA were extracted from B16F10 cells with SIRPA knockdown, overexpression or control and were subjected to mRNA paired-end sequencing by Novogene Co., LTD. Each cell line has three biological repeats.