INCLUDE Data Hub

The INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project is an NIH-wide collaboration that seeks to improve health and quality-of-life for people with Down syndrome. The INCLUDE Project Data Coordinating Center and partners created the INCLUDE Data Hub, a centralized data resource that allows access to large-scale clinical and multi-omics datasets specific to Down syndrome and supports collaborative, cloud-based analysis to accelerate scientific discoveries related to Down syndrome and its co-occurring conditions.唐氏综合征终生共病研究项目（INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE，简称INCLUDE）是一项美国国立卫生研究院（National Institutes of Health，NIH）全机构协作项目，旨在改善唐氏综合征（Down syndrome）患者的健康状况与生活质量。INCLUDE项目数据协调中心及其合作方共同搭建了INCLUDE数据枢纽（INCLUDE Data Hub），这一中心化数据资源可提供针对唐氏综合征的大规模临床与多组学数据集访问渠道，并支持基于云的协作分析，以加速与唐氏综合征及其共病相关的科学发现进程。

搜集汇总

背景与挑战

背景概述

INCLUDE Data Hub是由美国国立卫生研究院（NIH）支持的唐氏综合征研究数据中心，整合了大规模临床与多组学数据资源，支持云端协作分析。该中心汇集了42项研究、约1.58万名参与者及大量生物样本，涵盖人类三体项目、患者注册表等多个专项研究，旨在推动对唐氏综合征及其共病的科学发现。