ESSENTIAL ROLE OF THE INNATE IMMUNE ADAPTOR RIP2 IN THE RESPONSE TO OTITIS MEDIA

Two datasets are provided murine genes related to the NODs/Ripk2 pathway which is regulated during acute otitis media induced in mice. The first dataset provides the single-cell RNA-Seq expression values for pre-infection middle ear, and for the middle ear 6 hours after infection with nontypeable Haemophilus influenzae. The second dataset consists of gene array expression values from a complete episode of acute otitis media in wild type mice and middle ear tissue isolated at 3hr, 6hr, 12hr, 1, 2, 5, and 7 days post infection.

本研究提供了两个数据集，涉及与NODs/Ripk2通路相关的鼠类基因，该通路在由小鼠急性中耳炎诱导的过程中受到调控。第一个数据集提供了感染前中耳以及感染非典型流感嗜血杆菌后6小时的中耳的单细胞RNA测序表达值。第二个数据集包含了野生型小鼠急性中耳炎完整病程中的基因阵列表达值，以及感染后3小时、6小时、12小时、1天、2天、5天和7天时分离的中耳组织。