LR1 is a B cell-specific, sequence-specific duplex DNA binding activity which is induced in B cells carrying out class switch recombination. Here we identify several properties of LR1 which enable it

PubMed Central2000-07-15 更新60

Targets of EOMES in mouse CD4+ T cells. Targets of EOMES in mouse CD4+ T cells

细胞转录调控

EOMES基因

To gain mechanistic insights into how EOMES regulates CD4+ T-cell differentiation and function, we performed an RNA-seq analysis using Eomes-GFP reporter mice (Eomes+/GFP) to isolate GFP+ (EOMES+) and

NIAID Data Ecosystem40

Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells.. Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells.

乳腺肿瘤基因组学

细胞转录调控

Genomics has provided a detailed structural description of the cancer genome. Identifying oncogenic drivers that work primarily through dosage changes is a current challenge. Unrestrained proliferatio

NIAID Data Ecosystem70

Table_9_Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response.xlsx

受体信号通路

细胞转录调控

The nuclear receptor sub-family 4 group A (NR4A) family are early response genes that encode proteins that are activated in several tissues/cells in response to a variety of stressors. The NR4A family

NIAID Data Ecosystem50

Transcription Regulatory Networks of CD4 CD8 and CD14 cells in Patients of Type I Mellitus Diabetes

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