In-situ nano-CT study of bio-fabricated tendon-inspired electrospinning hierarchical scaffolds - for future medical applications (continuati

Biomedical scaffolding has been around for decades, however, the main criticism from medical aspects in applied (soft) tissue engineering comes down to the fact that artificial structures cannot carry sufficient hierarchical complexity that is comparable to the real biological bony or soft cartilage material. These prooves to be limitting in currently available technologies. In this work, a novel material produced by electrospinning micro-fibrils at different extrusion rates has proven to provide a sufficiently superior hierarchical structure. Before proceeding towards the mineralisation studies, the main steps lie in the full field mechanical characterisation of these structures, in situ. Consequently, two beamlines (ID16b and ID19) join their capacities. In this work, we will use the same setup as used in IH-LS-3489, on the ID19 beamline to complement the data already gathered on a nano-scale with data captured at a micro-scale (i.e., structural scale).