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Transcriptional profiling of beta cell specific CD8 T cells from non-obese diabetic mice

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NIAID Data Ecosystem2026-03-13 收录
下载链接:
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE151652
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资源简介:
CD8 T cells specific for beta cell antigen islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) were identified and isolated with NRP-V7 tetramers from the pancreatic draining lymph node and pancreas of non-obese diabetic (NOD) mice and used for single-cell RNA-seq and VDJ-seq. Activated CD8+NRP-V7+ T cells were sorted from the pancreatic lymph node and pancreas of non-obese diabetic mice using hashtags to identify individual mice and feature barcoding antibodies against CD44, CD127, CD62L, CD73, PD1, CD38, and CD39.
创建时间:
2022-02-04
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