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The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells

ChEBI2015-07-10 更新2026-07-12 收录

干细胞稳态调控

E3泛素连接酶功能

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70658 数据链接链接失效反馈

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The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells

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创建时间：

2015-07-10

干细胞转录调控

E3泛素连接酶功能

RNF12 is a developmental E3 ligase mutated in Tonne-Kalscheuer Syndrome patients. To identify the gene expression programme controlled by RNF12 activity in mouse embryonic stem cells we employ RNA-Se

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Sequencing of microRNA in spermatogonial stem cell enriched cell populations.. Mus musculus

干细胞miRNA表达谱

干细胞稳态调控

MicroRNAs (miRs) play a key role in the control of gene expression in a wide array of tissue systems where their functions include the regulation of self-renewal, cellular differentiation, proliferati

NIAID Data Ecosystem30

ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Homo sapiens

干细胞衰老

干细胞稳态调控

Loss of organelle homeostasis is a hallmark of aging. However, it remains elusive how this occurs at transcriptional levels. Here, we report that human mesenchymal stem cell (hMSC) aging is associated

NIAID Data Ecosystem20

Diversity in the Architecture of ATLs, a Family of Plant Ubiquitin-Ligases, Leads to Recognition and Targeting of Substrates in Different Cellular Environments

E3泛素连接酶功能

蛋白质相互作用

Ubiquitin-ligases or E3s are components of the ubiquitin proteasome system (UPS) that coordinate the transfer of ubiquitin to the target protein. A major class of ubiquitin-ligases consists of RING-fi

NIAID Data Ecosystem40

HUWE1 in map with focus on WWE

蛋白质结构解析

E3泛素连接酶功能

HUWE1 in map with focus on WWE Descriptor: E3 ubiquitin-protein ligase HUWE1 Authors: Hunkeler, M, Fischer, E.S. Deposit date: 2021-05-16 Release date: 2021-07-28 Last modified: 2024-05-29 Method: ELE

Protein Data Bank Japan2024-05-29 更新20

The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells

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