Crystal Structure of HIV-1 protease mutants D30N complexed with inhibitor GRL-0519
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Crystal Structure of HIV-1 protease mutants D30N complexed with inhibitor GRL-0519 Descriptor: (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, CHLORIDE ION, HIV-1 Protease, ... Authors: Zhang, H, Wang, Y.-F, Shen, C.H, Agniswamy, J, Weber, I.T. Deposit date: 2012-10-02 Release date: 2013-08-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease. J.Med.Chem., 56, 2013
创建时间：
2012-10-02
