Two-photon Dataset from All Mice for Sit & Goard: Distributed and Retinotopically Asymmetric Processing of Coherent Motion in Mouse Visual Cortex

Accompanying dataset for Sit KK, Goard MJ. Distributed and
Retinotopically Asymmetric Processing of Coherent Motion in Mouse Visual
Cortex.

This dataset contains all the two-photon recordings in L2/3 V1 for all mice used.

See related data in collection here: https://doi.org/10.35092/yhjc.c.5018363

The purpose of these data is to understand the organization of neural activity in response to coherent motion in the murine visual cortex.

The manuscript associated with these data is Sit KK, Goard MJ. Distributed and Retinotopically Asymmetric Processing of Coherent Motion in Mouse Visual Cortex.

ABSTRACT
Perception of visual motion is important for a range of ethological behaviors in mammals. In primates, specific visual cortical regions are specialized for processing of coherent visual motion. However, whether mouse visual cortex has a similar organization remains unclear, despite powerful genetic tools available for measuring population neural activity. Here, we use widefield and 2-photon calcium imaging of transgenic mice to measure mesoscale and cellular responses to coherent motion. Imaging of primary visual cortex (V1) and higher visual areas (HVAs) during presentation of natural movies and random dot kinematograms (RDKs) reveals varied responsiveness to coherent motion, with stronger responses in dorsal stream areas compared to ventral stream areas. Moreover, there is considerable anisotropy within visual areas, such that neurons representing the lower visual field are more responsive to coherent motion. These results indicate that processing of visual motion in mouse cortex is distributed heterogeneously both across and within visual areas.