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Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST

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Protein Data Bank Japan2024-02-07 更新2026-04-19 收录
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Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Descriptor: Mast/stem cell growth factor receptor Kit, ~{N}-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine Authors: Graedler, U, Lammens, A. Deposit date: 2022-05-19 Release date: 2023-02-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.119 Å) Cite: Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors. J.Med.Chem., 66, 2023

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2022-05-19
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