Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate
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Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate Descriptor: ({[6-(4-cyclopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methanediyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... Authors: Park, J, Leung, C.-Y, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2013-06-04 Release date: 2014-01-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. J.Med.Chem., 56, 2013
创建时间：
2013-06-04
